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Sodium oxybate: concomitant administration of codeine and sodium oxybate may well result in elevated CNS despair and/or respiratory depression and/or hypotension.

It is critical that you choose to fully grasp the rules of your Opioid Analgesic REMS software to stop habit, abuse, and misuse of codeine.

- Never acquire for for a longer period than directed by your prescriber. - Getting codeine frequently for many years can result in habit, which might lead to you to definitely experience restless and irritable once you cease the tablets.

Use must be avoided in individuals with raised intracranial pressure or head harm (Along with the potential risk of respiratory melancholy and amplified intracranial pressure, may perhaps have an impact on pupillary and other responses important for neurological assessment).

No enough experiments are done in animals to determine whether acetaminophen and codeine have a potential for carcinogenesis or mutagenesis. No ample scientific tests are already done in animals to determine no matter whether acetaminophen has a potential for impairment of fertility.

The risk of acute liver failure is larger in men and women with fundamental liver disease As well as in individuals who ingest alcohol when using acetaminophen.

Danger from concomitant usage of sedative medicines which include benzodiazepines or similar medicines Concomitant utilization of Codeine Phosphate Tablets and sedative medicines like benzodiazepines or linked medication may perhaps cause sedation, respiratory melancholy, coma and Dying. Due to these risks, concomitant prescribing Using these sedative medicines ought to be reserved for clients for whom different therapy options are not possible.

Employing this medication while you're pregnant might bring about severe undesired outcomes, like neonatal withdrawal syndrome inside your newborn infant. Explain to your medical professional instantly if you think you're Expecting or if you intend to become pregnant whilst using this medicine.

This drugs has become prescribed for you only. Usually do not move it on to others. It may well harm them, regardless of whether their signs of health issues are the same more info as yours.

If you don't Use a drug take-back again site in your area, flush any unused narcotic drugs down the bathroom. Test your local drug retail outlet and clinics for just take-again locations. You may also Test the DEA Web page for areas. Here's the url towards the FDA safe disposal of medicines Web page:

For Delicate to Average Discomfort Codeine must be employed at the lowest successful dose for your shortest period of time. This dose might be taken, as many as four times every day at intervals of not below 6 several hours. Most daily dose of codeine must not exceed 240 mg.

Constipation is a typical side outcome of the two codeine and hydrocodone more info use and often carries on through procedure. People might get stool softeners and improve their fluid ingestion to help you decrease this facet impact.

Codeine really should be made use of at the bottom powerful dose for the shortest period of time. This dose may be taken as much as four periods every day at intervals of not below six hrs. Optimum daily dose of codeine mustn't exceed 240mg.